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Estrogen Blocking Supplements Toremifene Citrate Powder Clomid For Bodybuilder

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Estrogen Blocking Supplements Toremifene Citrate Powder Clomid For Bodybuilder

Brand Name : Guangzhou Huao
Model Number : 89778-27-8
Certification : IOS9001 ,Kosher, COA,SGS,USP
Place of Origin : Guangzhou China
MOQ : 10g
Price : Negotiation
Payment Terms : T/T, Western Union,Paypal, MoneyGram,Bitcoin,Bank Transfer
Supply Ability : 1000kg/month
Delivery Time : 4-7 days
Packaging Details : Foil Bag or Tin, Perfect Discreet, as Required
Assay : >99%
transport packing : Foil Bag or Tin, Perfect Discreet, as Required
Reship Policy : Reship Free
samples : Available
Appearance : white crystalline powder
E-mail : evan@ycphar.com
Whatsapp : +8615622635381
Market : Global
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Anti Estrogen Steroids Toremifene Citrate Powder Clomid For Bodybuilder
English NameToremifene citrate
CAS89778-27-8
Molecular formulaC32H36ClNO8
Molecular weight598.08
Related categoriespharmaceutical raw materials; cell biology; APIs; pharmaceutical intermediates; XYREM; antineoplastic drugs and immunosuppressive agents; intermediates; Analgesics; antibiotics; antineoplastic agents

Summary
Toremifene citrate (toremifene citrate), a chemical called Z-2-[4- (4- -1 2- two phenyl chloride, -1-) butylidene phenoxy]]-N N- two single methyl amine citrate, is developed by Finland Farmos company in 1979 of a new generation of anti estrogen anti-tumor drugs, is the development of non steroidal derivatives three kinds of styrene, and for the first time in 1988 in Finland listed non steroidal anti estrogen anti-tumor drugs, mainly used for the treatment of breast cancer.

pharmacological action
Toremifene combined with acid citrate and estrogen receptor, can produce estrogenic or anti estrogenic effects, or also has two effects, it mainly depends on the duration, animal species, sex and target organ of the set. In general, non steroidal three styrene derivatives are mainly estrogenic in humans and rats and exhibit estrogenic effects in mice. Postmenopausal breast cancer patients after clomiphene Torre total cholesterol induced serum and low density lipoprotein (LDL) moderate decline. Toremifene citrate and estrogen competitively with breast cancer cells and estrogen receptor combination, prevent cancer cell DNA synthesis and proliferation induced by estrogen. Some experimental tumors using high-dose toremifene citrate, showing toremifene citrate with non estrogen dependent antitumor effects. The anti breast cancer effect of toremifene citrate is mainly anti estrogenic effects, may also have other anticancer mechanisms (change of tumor gene expression and secretion of growth factor, cell apoptosis and cell cycle kinetics influence).

Adverse reaction
Adverse reactions are usually mild, mostly hormone like reactions. In clinical trials, the most common adverse reactions for facial flushing (20%), other common adverse reactions are sweating (14%), nausea (8%), leucorrhea (8%), head (4%), edema (3%), pain (2%) and vomiting (2%). A lower incidence of adverse reactions include 1%: vaginal bleeding, chest pain, fatigue, headache, back pain, skin discoloration, weight gain, insomnia, constipation, dyspnea, partial paralysis, tremor, itching, dizziness, anorexia, reversible corneal opacity and weakness are thromboembolism and in some cases reported elevated transaminase. Rare, unable to decide whether the adverse reactions and Shurui related: dermatitis, alopecia, emotional instability, depression, jaundice and stiff. About 3% of patients discontinued treatment due to adverse reactions, the most common reason for discontinuation of nausea and vomiting, dizziness, hypercalcemia and vaginal bleeding, found at the beginning of treatment of hypercalcemia may be associated with bone metastasis.
The toremifene citrate overview, preparation methods, pharmacological effects and clinical application is edited by Chemicalbook Ding Hong.

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