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Men Hair Loss Treament Anti Estrogen Steroids Tamoxifen Citrate Powder Nolvadex

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Men Hair Loss Treament Anti Estrogen Steroids Tamoxifen Citrate Powder Nolvadex

Brand Name : Guangzhou Huao
Model Number : 54965-24-1
Certification : IOS9001 ,Kosher, COA,SGS,USP
Place of Origin : Guangzhou China
MOQ : 10g
Price : Negotiation
Payment Terms : T/T, Western Union,Paypal, MoneyGram,Bitcoin,Bank Transfer
Supply Ability : 1000kg/month
Delivery Time : 4-7 days
Packaging Details : Foil Bag or Tin, Perfect Discreet, as Required
Assay : >99%
transport packing : Foil Bag or Tin, Perfect Discreet, as Required
Reship Policy : Reship Free
samples : Available
Appearance : white crystalline powder
E-mail : evan@ycphar.com
Whatsapp : +8615622635381
Market : Global
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Anti Estrogen Steroids Tamoxifen Citrate Powder Nolvadex for men hair loss treament
Brief introduction
English NameTamoxifen citrate
CAS number54965-24-1
Molecular formulaC32H37NO8
Weight563.64
EINECS number259-415-2
English synonyms1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene, citrate; (z) -2- (4- (1,2-diphenyl-1-butenyl) phenoxy) -n, n-dimethylethanamine
Related categoriesantineoplastic drugs, antitumor drugs and immunosuppressive agents; antibiotics; raw materials; small molecule inhibitors; Inhibitors; small molecule inhibitors; natural products; antineoplastic

know more about Tamoxifen Citrate
Summary
Tamoxifen citrate (tamoxifen, tamoxifen citrat e, referred to as TCT), is a kind of estrogen (estrogen) antagonists, non steroid anti estrogen drugs in vivo, and estrogen (estradiol) competition, combined with estrogen receptor in breast cancer cells, thereby inhibiting the effect of estrogen on cancer cells and tumor cell growth retardation, and anti-cancer effects. Clinically, it is commonly used in the treatment of various types of breast cancer, especially for postmenopausal women with low estrogen receptor and progesterone receptor and low prostate specific antigen levels.

Mechanism of action
TCT has CIS trans isomer, and its cis isomer shows weak estrogen effect, whereas trans isomer has anti estrogen effect. When tamoxifen was used early or at low concentrations, it was combined with estrogen receptor (ER) in the cytoplasm, thus showing a weak estrogen effect. When TCT enters the nucleus, it inhibits the transcription and synthesis of nuclear ER and produces long-lasting anti estrogen effects. Many new functions of TCT have been found to be related to the mechanism of action, the membrane regulation mechanism, that competes beyond estrogen receptors. TCT, as a membrane regulator, can reduce cell circulation. On the basis of this, it can also be used as an antioxidant to protect cell membranes and human LDL from oxidative damage.

clinical application

1. breast cancer treatment.
2. prevention of breast cancer.
3. antitumor and multidrug resistance.
Tamoxifen citrate by reducing membrane circulation and enhance cell binding site between the rigid, cancer transfer promoter and various activating enzyme concentration and activity decreased, so as to inhibit or prevent cancer cell growth and metastasis. In addition, it can also promote the secretion of tumor cells around the negative growth factor transforming growth factor TGF- G, curb unlimited reproduction and can inhibit cancer cells; produced by human neutrophils caused by H2O2 DN A base oxidation damage, so the other malignant tumors of breast cancer treatment and beyond are the benefits of prevention, has been applied to brain tumor, liver cancer, prostate cancer and other cancer treatment. In addition, tamoxifen citrate can reduce the release of P170 glycoprotein on the cell membrane by reducing the membrane mobility, and improve the effective concentration of cytotoxic drugs in cells and reduce drug resistance.

4. heart protection.
The overview, mechanisms, and clinical applications of tamoxifen citrate were edited by Chemicalbook's Ding Hong editor. (2015-12-02)
Adverse reaction
Common nausea, vomiting, facial flushing and other minor adverse reactions.

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