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Local Anesthetic Agents Tetracaine Hydrochloride Powder CAS 136-47-0

Guangzhou Huao Chemical Co.,Ltd
Guangzhou Huao Chemical Co.,Ltd
City: Guangzhou
Province/State: Guangdong
Country/Region: China
Tel: 86-188-26120470
Contact Person:Mr Adam

Local Anesthetic Agents Tetracaine Hydrochloride Powder CAS 136-47-0

Brand Name : Guangzhou Huao
Model Number : 136-47-0
Certification : IOS9001 ,Kosher, COA,SGS,USP
Place of Origin : Guangzhou China
MOQ : 10g
Price : Negotiation
Payment Terms : T/T, Western Union,Paypal, MoneyGram,Bitcoin,Bank Transfer
Supply Ability : 1000kg/month
Delivery Time : 4-7 days
Packaging Details : Foil Bag or Tin, Perfect Discreet, as Required
Assay : >99%
transport packing : Foil Bag or Tin, Perfect Discreet, as Required
Reship Policy : Reship Free
samples : Available
Appearance : white crystalline powder
E-mail : evan@ycphar.com
Whatsapp : +8615622635381
Market : Global
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Local Anesthetic Powder Tetracaine hydrochloride Powder for Relieve Pain
Basic details
English NameTetracaine hydrochloride
CAS136-47-0
Molecular formulaC15H25ClN2O2
Molecular weight300.82
EINECS205-248-5

Introduction

Tetracaine is really a weak base, therefore, significant changes in the interest rate of ionised lipid soluble drug uptake will occur with adjustments to the acid base balance.

In vitro studies show that tetracaine includes a high affinity for melanin, therefore, differences in use of action could possibly be expected between deeply pigmented eyes and much less pigmented eyes.

The principal site of metabolism for tetracaine will be the plasma. Pseudocholinesterases inside the plasma hydrolyse tetracaine to 4-aminobenzoic acid. Unmetabolised drug is excreted inside the urine.

Tetracaine hydrochloride can be used being a local anaesthetic which acts by reversibly blocking the propagation and conduction of nerve impulses along nerve axons. Tetracaine stabilises the nerve membrane, preventing the increase in sodium permeability necessary for the production of an action potential.

Usage:

1)Tetracaine (INN, often known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is often a
potent local anesthetic with the ester group. It's mainly used topically in ophthalmology so that as an
antipruritic,
and contains been used in spinal anesthesia.In biomedical research, tetracaine is employed to change the function of calcium release channels (ryanodine receptors) that control the making of calcium from
intracellular stores. Tetracaine is definitely an allosteric blocker of channel function. At low concentrations,
tetracaine causes a preliminary inhibition of spontaneous calcium release events, while at high
concentrations, tetracaine blocks release completely.


2.)The efficacy profile of lidocaine as a local anesthetic is characterized by an immediate onset of action and intermediate time period of efficacy. Therefore, lidocaine would work for infiltration, block, and surface anesthesia. Longer-acting substances like bupivacaine are now and again given preference for subdural and epidural anesthesias; lidocaine,though, has the advantage of an immediate start action.
In dental anesthesia, a member of family insensitivity to lidocaine can occur for anatomical reasons as a result of unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.

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