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16595-80-5 Pharmaceutical Raw Materials Levamisole hydrochloride Powder

Guangzhou Huao Chemical Co.,Ltd
Guangzhou Huao Chemical Co.,Ltd
City: Guangzhou
Province/State: Guangdong
Country/Region: China
Tel: 86-188-26120470
Contact Person:Mr Adam

16595-80-5 Pharmaceutical Raw Materials Levamisole hydrochloride Powder

Brand Name : Huao(Whatsapp:+8615622635381)
Model Number : 16595-80-5
Certification : IOS9001 ,Kosher, COA,SGS,USP
Place of Origin : Guangzhou China
MOQ : 10g
Price : Negotiation
Payment Terms : T/T, Western Union,Paypal, MoneyGram,Bitcoin,Bank Transfer
Supply Ability : 1000kg/month
Delivery Time : 4-7 days
Packaging Details : Foil Bag or Tin, Perfect Discreet, as Required
Assay : >99%
transport packing : Foil Bag or Tin, Perfect Discreet, as Required
Reship Policy : Reship Free
samples : Available
Appearance : white crystalline powder
E-mail : evan@ycphar.com
Whatsapp : +8615622635381
Market : Global
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Pharmaceutical Raw Materials Levamisole hydrochloride Powder 16595-80-5


Product nameLevamisole hydrochloride
Other nameL-Tetramisole
CAS16595-80-5
MFC11H12N2S.HCl
MW240.75
Molecular structureLevamisole hydrochloride Pharmaceutical Intermediates To Deficiencies Of The Immune System
Assay99%
AppearanceWhite or almost white crystalline powder crystalline granular powder
Usagein the regulation of immune responses or deficiencies of the immune system

Levamisole hydrochloride Description

Uses as anthelmintics, suitable for animal roundworm, hookworm and other treatment.
Use of the goods is the drive intestinal insects. The activity of levamisole is about twice that of racemic, and the toxicity and side effects are also low. Levamisole can make roundworm muscle paralysis after excrement with the feces. Mainly used for anti-roundworm and anti-hook insects.
Use for the drive roundworm, hookworm, Malayi insect infection
Uses levamisole hydrochloride is a swine medicine. The activity of levamisole is about twice that of racemic, and the toxicity and side effects are also low. Levamisole can make roundworm muscle paralysis after excrement with the feces. Mainly used for anti-roundworm and anti-hook insects.


Levamisole hydrochloride Application

Production methods from the racemic four imidazole (C11H12N2S, [5036-02-2]) split, alkaline hydrolysis, derived salt. Dibenzoyl-D-tartaric anhydride was boiled with water and hydrolyzed for 40 min. Cooling to about 45 ℃, with sodium hydroxide solution to adjust the pH to 7.5, adding racemic four imidazole. After cooling for half an hour to 10 ℃, filter, washed with levamisole p-benzoyl tartrate. The pH was adjusted to 9 with sodium hydroxide solution, filtered and washed with levamisole. The pH was adjusted to 3-4 with hydrochloric acid, decolorized with activated charcoal, filtered, the filtrate was concentrated to dryness, and acetone was cooled to 0 ° C. Precipitation crystallization. Filtered and dried to give levamisole hydrochloride. When the dextroylimidazolium terephthalate is separated, the resulting mother liquor is a mixture of dextrorolidazole free base and racemic to obtain racemic tetrazole. Racemic tetramidazole can also be resolved using p-toluenesulfonylglutamic acid or dextro camphorsulfonic acid.
Production methods to racemic four imidazole as raw materials, the split, alkaline hydrolysis, acidification derived from salt.
Dibenzoyl-D-tartaric anhydride was boiled in water for 40 min, hydrolyzed and neutralized with sodium hydroxide solution to pH 7.5, and racemic tetramidazole was added. Levamisole and dibenzoyl tartaric acid to produce salt and precipitate. After separation, add sodium hydroxide solution to pH = 9, decomposition of levamisole. And then dissolved in dilute hydrochloric acid solution, decolorized by activated carbon, the filtrate concentrated near dry, add acetone cooled t


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